Storyline: Life As We Know It 2010 Holly Berenson (Katherine Heigl) is the owner of a small Atlanta bakery, and Eric Messer (Josh Duhamel), (often just known as "Messer") is a promising television technical sports director for the Atlanta Hawks. Their best friends Peter (Hayes MacArthur), an attorney, and Alison Novak (Christina Hendricks) set them up on a blind date that goes horribly wrong, and results in both hating each other. As the years go by, Peter and Alison get married, and have a baby girl named Sophie Christina, and select Holly and Messer as godparents of Sophie. They tolerate each other, but still tease and banter.Shortly after Sophie's first birthday, Peter and Alison are killed in a car crash. Holly and Messer learn that in their friends' wills, they were named Sophie's joint guardians. Holly and Messer must put their differences aside and move into Sophie's home to care for her. Living together proves to be a struggle. One night, Holly leaves Sophie with Messer while she covers an important catering job - the same night that he is given the opportunity to direct a big basketball game. Messer takes Sophie to work, but she constantly distracts him with her crying. Messer makes a big mistake at the end of the game and thinks his chances of being promoted are gone. When they get home, Messer and Holly argue, but later they make up.Holly meets Sam (Josh Lucas), Sophie's pediatrician, and finds herself attracted to him. They arrange a date, which is cut short when Messer calls to tell Sam that Sophie has a high fever. Sam and Holly go to the hospital, and Messer sees Holly kiss Sam....
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